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Complementary functional studies, including B-cell subset analysis, avidity maturation assessment, and effector function evaluation, are essential, particularly given our in silico predictions of synergistic TLR3/78 signaling and multi-epitope vaccine design optimization

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The formation of RONS triggers inflammation, but on the other hand, inflammation also triggers the formation of RONS, which ends in oxidative stress, as described in Figure 2 (33)